
Mr. Muscles came to be from the mind of Jerry Siegel in March 1956. Charlton threw in the towel on Blue Beetle (1955), and kept the numbering from his magazine as they replaced him with Mr. Muscles. Bill Fraccio was the artist for the first issue, #22. For the second and last issue, Charles Nicholas and John Forte were in charge of the art with Siegel still doing all the stories.
It is important to point out this is the ad in the front of the comic. Both issues are full of ads just like these, making it seems like a big advisement.

Not only did Mr. Muscles have a sidekick, but there was a Miss Muscles too! She only lasted two pages in issue #22.

You can read the origin story from #22 on scans_daily along with Miss Muscles' story (with a backup link here). You can read the story of Kid Muscle and Mr. Muscles vs. Jake Armbuster on dreamwith.
The final story in issue #23 is call "Steeple Jack," but more on him in another post.
In the way of more information...there isn't much....
International Catalog of Superheroes: Mr. Muscles
Oddball Comics - Mr. Muscles