Señorita Rio, Rita Farrar or Consuela Maria Ascencion De Las Vegas, was an American secret agent. She disguised herself as a Brazilian entertainer, taking advantage of her Latin background to go in to place other agents could blend in. She was often assigned to root out fascists Central and South America during World War II.
Senorita Rio appeared in #19-71 (1942 to 1951). The only exception is #69 when the comic dropped from 52 pages to 36. She has a lot of big name artist throughout her run: Nick Cardy, Lily Renee, Jack Kamen, and Bob Lubbers. Most notable due to the amount of time she spend on it is Lily Renee, see her interview with TCJ below.
Further info after the comics!
Fight Comics #19 (June 1942) "Swastika Web" [First appearance] Art by Nice Cardy Read it here OR take it page by page - Page 01// 02 // 03 // 04// 05 // 06 // 07 // 08
Fight Comics #47 (Dec. 1946) "Horror's Hacienda" Story by "Morgan Hawkins" (often used pen name, unknown owner); Art by Lily Renee Read it here or see it on comics19-at flicker. (Note that the pages are backwards.) And checkout the rest of Fight Comics #47 on a Highlight Reel.
Oddball Comics has a recap of “The Santo Bello Assignment” from Knockout Adventures #1
Rio Rita (Toonpeida)
Rio Rita Profile (FemForce)
The Comics Journal - Lily Renée - An interview with the interesting woman who did so much of the art for the strip.